The human P2Y family of metabotropic receptors include eight accepted members, including P2Y1,2,4,6,11,12,13,14. P2Y2,4,11 are activated mainly by nucleoside triphosphates whereas P2Y1,6,12,13 are activated by nucleoside diphosphates. P2Y11 couples both to Gq/11 and to Gs and is expressed in a variety of tissues including epithelia, smooth muscle, granulocytes, dendritic cells and kidney.
Human P2Y11 Purinergic Receptor Cell Line
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