The human TRPM4 gene encodes the pore-forming subunit of TRPM4, a non-selective, cation-permeable channel expressed in lymphocytes, heart, vascular smooth muscle, intestine and prostate. A gain-of-function mutation in TRPM4 is associated with progressive familial heart block type I. TRPM4 channels are therapeutic targets in inflammation and immune disorders.
Human TRPM4 Channel Cell Line
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