Human V1a Vasopressin Receptor Cell Line

The pituitary hormone vasopressin (AVP) is a cyclic nonapeptide that acts by binding to a family of vasopressin receptors that includes the V1a, V1b and V2 receptors. V1a receptors have been shown to be expressed in vascular smooth muscle, hepatocytes, various blood cells, brain and retina. These receptors mediate cell proliferation, platelet aggregation, coagulation factor release and glycogenolysis. This cell line is useful for both radioligand binding and for functional assays.

Catalog Number

A649

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