The pituitary hormone vasopressin (AVP) is a cyclic nonapeptide that acts by binding to a family of vasopressin receptors that includes the V1a, V1b and V2 receptors. V1b receptors are expressed in the anterior pituitary where they mediate ACTH release. Selective V1b antagonists have been shown to have anxiolytic and antidepressant effects. This cell line is useful for both radioligand binding and for functional assays.
Human V1b Vasopressin Receptor Cell Line
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