Serotonin (5-hydroxytryptamine, 5-HT) exerts its many physiological effects through 13 distinct receptor subtypes in humans. These subtypes fall into seven structurally-defined classes (5-HT1 to 5-HT7). 5-HT2b receptors are expressed in the brain, vasculature, smooth muscle, uterus and stomach. This receptor has been used as a target for developing drugs to treat migraine, anxiety and irritable bowel syndrome.
Mouse 5-HT2B Serotonin Receptor Membranes
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