Rat CB1 Cannabinoid Receptor Membranes

The CB1 cannabinoid receptor expressed primarily in brain is a target for cannabinoids (Matsuda et al., 1990), the psychoactive ingredients of marijuana. Other members of the cannabinoid family of receptors include CB2, expressed primarily in the periphery, and GPR55 (Ryberg, 2007). CB1 receptor activation receptor inhibits adenylate cyclase through Gi. CB1 receptor plays a significant role in modulation of food intake (Cota, 2007).

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