Charles River Partner Portal - NA

Charles River is a key provider of research models and services. Our goal is to provide the highest standards of service and quality in everything we do, so that the scientists can be empowered to focus on what matters most – furthering their understanding of biomedical science.

Do you have a question or want to brainstorm? We can support your research models and services needs. 

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Gain Animal Health Insights in Just 15 Minutes with Our Fast Tracks Learning Series

Are you keeping up with the crucial information you need to protect the health and security of your most crucial research asset – your animal models?

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Charles River Offers Embryology Services & Contract Breeding
of Genetically Engineered Mice and Rats

Charles River provides a complete portfolio of embryology services including cryopreservation, rederivation, model creation and rapid colony expansion. 

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Model Evaluation Program

Do you wish to trial a model to test suitability before making a purchase? Explore our free animal model evaluation program.

Trial a Model
 

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If you need a highly immunodeficient mouse model...

Our NCG mouse model is the most highly immunodeficient mouse and the model of choice for cancer xenograft modelling, stem cell biology, humanized mice, and infectious disease research.

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Academic Welcome Program

Charles River's Academic Welcome Program is designed to provide new inquiring researchers with special discounts and technical support for their next studies. These program offers are valid through December 31, 2021.


NCI Grantee Pricing

Our NCI 2021 catalog offers grantees a reduced price on popular models. Pricing for NCI grantees will not increase in 2021.

Download our catalog using your organization's email account to view research model discounts and terms and conditions for your organization. If you have additional questions, contact your account manager for more information.

Immunodeficient models are important for a variety of research applications. The chart below, showing immunodeficiency and phenotypes, can be used to help identify the model that best fits your research needs. Your organization receives preferential pricing on many of our immunodeficient models.

Strain
Species
T-Cell-Deficient
B-Cell-Deficient
NK-Cell-Deficient
Hair Coat
RNU Nude Rat YES NO NO NO
Athymic Nude Mouse YES NO NO NO
CD-1® Nude Mouse YES NO NO NO
NU/NU Nude Mouse YES NO NO NO
BALB/c Nude Mouse YES NO NO NO
SCID Hairless Congenic (SHC™) Mouse YES YES NO NO
SCID Hairless Outbred (SHO®) Mouse YES YES NO NO
Fox Chase SCID® Mouse YES YES NO YES
NCI NOD SCID® Beige Mouse YES YES NO YES
Fox Chase SCID® Beige Mouse YES YES Impaired YES
NIH-III Nude Mouse YES YES Impaired NO
NOD SCID Mouse YES YES Impaired YES
NCG Mouse YES YES YES YES

 

Humanized Models
There are several options available if your research requires humanized models, including: 

•   CD34+ Humanized Mouse Model
•   PBMC Humanized Mouse Model
•   NCG/PBMC Select Humanization Kit

Access our NCG Model Capabilities and Applications Brochure to learn more about the benefits of using these specialized models. Researchers at your organization receive special pricing. If you're new to the NCG, ask your account manager about our evaluation program. 

Xenograft Collection
Our xenograft data collection is designed to help you decide the most appropriate animal model to use when designing a study. To assist you in expediting your model selection process, we have compiled xenograft data on the following models.  
Charles River Oncology Resources
•   Immunodeficient Models Xenograft Data Collection 
•   Immunodeficient Mice
•   Humanized Mice
•   Tumor Model Compendium

1. Genetically Engineered Models and Services (GEMS) 
Our GEMS division offers a wide variety of services from breeding to model creation. Our decades of experience and vast network of vivariums around the world gives us the opportunity to offer an unparalleled selection of custom models and services to meet your unique needs. Researchers at your organization receive many discounts off services provided by GEMS. Use our quoting tool to view the best price for your study.

Services Offered
•   Breeding
•   Model creation
•   Embryology
•   Quarantine
•   Genetic testing 


2. Surgical Models and Services
•   Vascular catheterization
•   Non-vascular catheterizations
•   Cardiovascular surgery
•   Neurological procedures
•   Soft-tissue Procedures
•   Device implants
•   Biospecimens

3. Diagnostic Services
•   Non-GLP cell line/research biologics screening
•   Microbiome testing with next generation sequencing 

 

Guidebooks
Check out our free, digital laboratory animal guidebooks on infection surveillance of rodents and colony management for mice and rats in the Charles River Guidebook Series.
 
Publications
•   Targeting the Human MUC1-C Oncoprotein with an Antibody-Drug Conjugate
JCI Insight, 2018)

•   Clodronate Improves Survival of Transplanted Hoxb8 Myeloid Progenitors with Constitutively Active GMCSFR in Immunocompetent Mice
Molecular Therapy – Methods & Clinical Development, 2017)

•  Accumulation of Cytoplasmic CDC25A in Cutaneous Squamous Cell Carcinoma Leads to a Dependency on CDC25A for Cancer Cell Survival and Tumor Growth
(Cancer Letters, 2017)
Webinars
•   Upcoming
•   On demand
•   GEMS webinars, covering cryopreservation to CRISPR/Cas9 model creation
•   Germ-Free Colony Management
•   Maintaining a Static Microbiome Across Research Projects: Can It Be Done?
•   Immuno-oncology/oncology
•   Continuous Improvements in Humanized Mouse Models
•   Finding the Right Humanized Model for Your Research
Seminar Topics (Personalized Trainings)
Our team of Research Model Specialists offer free educational seminars on a variety of topics, including: 
•   Immunodeficient and humanized animal models for oncology studies
•   Using and applying our vascular catheter models
•   Others, upon request
Posters
•   Common Rodent Health Conditions
•   Metabolic Diseases
•   Immunodeficient Mice
Regulatory Training and Continuing Professional Development
Charles River Insourcing Solutions℠ provides high-quality training and continuing professional development for veterinarians, scientists, lab technicians, and anyone else working in the field of animal research. Courses for rodents, zebrafish, and other species include personal license holder categories PIL A, B & C, and a PPL Module for project license applicants. CPD courses include NACWO, NTCO, a law refresher course, and more. 

In person and eLearning options are both available. See our upcoming courses at a location near you, or contact your account manager about delivering a course at your facility.
 
ARRIVE Guidelines
Read more on ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments), which include clear guidance on research model nomenclature guidelines and other reporting criteria. 

 

How can I get information about special offers on research model and services?
Please contact your account manager.
What is your evaluation program?
Our evaluation program offers free research models to clients that have not used a strain to evaluate the quality and compatibility of our animal models with their research before making a commitment. Whether you have a new research protocol, are conducting or fine-tuning a pilot study, or simply exploring the opportunity to switch to a new animal model, this program can help you make the right choice.
Do you have any COVID-19 related resources? 
Yes. Take a look at our COVID-19 resources. A popular model for work on SARS-CoV-2 is Syrian Hamsters.
Do you have aged C57BL/6 mice?
Yes. We have an aged C57BL/6 colony. 
Are health reports available?
Yes. Health reports are available for research animal models bred by Charles River in North America.
Where can I find additional educational resources? 
See our expanded digital resources.
Do you provide information on infectious agents? 
Yes. Understanding infectious agents that can contaminate your research animal facility allows you to develop a plan to manage or prevent an outbreak. Our technical sheets contain information on viruses, bacteria/fungi, and parasites prevalent in laboratory animals.
When can I expect delivery? 
Please check with customer service. 
How do I contact Charles River? 
Please contact our US client services team directly:
•   Email: [email protected]
•   Phone: 1-800-522-7287