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Charles River Offers Embryology Services & Contract Breeding
of Genetically Engineered Mice and Rats
Model Evaluation Program
Do you wish to trial a model to test suitability before making a purchase? Explore our free animal model evaluation program.
Trial a Model
If you need a highly immunodeficient mouse model...
Our NCG mouse model is the most highly immunodeficient mouse and the model of choice for cancer xenograft modelling, stem cell biology, humanized mice, and infectious disease research.
Academic Welcome Program
Charles River's Academic Welcome Program is designed to provide new inquiring researchers with special discounts and technical support for their next studies. These program offers are valid through December 31, 2021.
NCI Grantee Pricing
Our NCI 2021 catalog offers grantees a reduced price on popular models. Pricing for NCI grantees will not increase in 2021.
Download our catalog using your organization's email account to view research model discounts and terms and conditions for your organization. If you have additional questions, contact your account manager for more information.
Immunodeficient models are important for a variety of research applications. The chart below, showing immunodeficiency and phenotypes, can be used to help identify the model that best fits your research needs. Your organization receives preferential pricing on many of our immunodeficient models.
|SCID Hairless Congenic (SHC™)||Mouse||YES||YES||NO||NO|
|SCID Hairless Outbred (SHO®)||Mouse||YES||YES||NO||NO|
|Fox Chase SCID®||Mouse||YES||YES||NO||YES|
|NCI NOD SCID® Beige||Mouse||YES||YES||NO||YES|
|Fox Chase SCID® Beige||Mouse||YES||YES||Impaired||YES|
• CD34+ Humanized Mouse Model
Our xenograft data collection is designed to help you decide the most appropriate animal model to use when designing a study. To assist you in expediting your model selection process, we have compiled xenograft data on the following models.
|Charles River Oncology Resources
• Immunodeficient Models Xenograft Data Collection
• Immunodeficient Mice
• Humanized Mice
• Tumor Model Compendium
1. Genetically Engineered Models and Services (GEMS)
2. Surgical Models and Services
• Vascular catheterization
• Non-vascular catheterizations
• Cardiovascular surgery
• Neurological procedures
• Soft-tissue Procedures
• Device implants
3. Diagnostic Services
Check out our free, digital laboratory animal guidebooks on infection surveillance of rodents and colony management for mice and rats in the Charles River Guidebook Series.
• Targeting the Human MUC1-C Oncoprotein with an Antibody-Drug Conjugate
JCI Insight, 2018)
• Clodronate Improves Survival of Transplanted Hoxb8 Myeloid Progenitors with Constitutively Active GMCSFR in Immunocompetent Mice
Molecular Therapy – Methods & Clinical Development, 2017)
• Accumulation of Cytoplasmic CDC25A in Cutaneous Squamous Cell Carcinoma Leads to a Dependency on CDC25A for Cancer Cell Survival and Tumor Growth
(Cancer Letters, 2017)
• On demand
• GEMS webinars, covering cryopreservation to CRISPR/Cas9 model creation
• Germ-Free Colony Management
• Maintaining a Static Microbiome Across Research Projects: Can It Be Done?
• Continuous Improvements in Humanized Mouse Models
• Finding the Right Humanized Model for Your Research
|Seminar Topics (Personalized Trainings)
Our team of Research Model Specialists offer free educational seminars on a variety of topics, including:
• Immunodeficient and humanized animal models for oncology studies
• Using and applying our vascular catheter models
• Others, upon request
• Common Rodent Health Conditions
• Metabolic Diseases
• Immunodeficient Mice
|Regulatory Training and Continuing Professional Development
Charles River Insourcing Solutions℠ provides high-quality training and continuing professional development for veterinarians, scientists, lab technicians, and anyone else working in the field of animal research. Courses for rodents, zebrafish, and other species include personal license holder categories PIL A, B & C, and a PPL Module for project license applicants. CPD courses include NACWO, NTCO, a law refresher course, and more.
In person and eLearning options are both available. See our upcoming courses at a location near you, or contact your account manager about delivering a course at your facility.
Read more on ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments), which include clear guidance on research model nomenclature guidelines and other reporting criteria.
|How can I get information about special offers on research model and services?
Please contact your account manager.
|What is your evaluation program?
Our evaluation program offers free research models to clients that have not used a strain to evaluate the quality and compatibility of our animal models with their research before making a commitment. Whether you have a new research protocol, are conducting or fine-tuning a pilot study, or simply exploring the opportunity to switch to a new animal model, this program can help you make the right choice.
|Do you have any COVID-19 related resources?
Yes. Take a look at our COVID-19 resources. A popular model for work on SARS-CoV-2 is Syrian Hamsters.
|Do you have aged C57BL/6 mice?
Yes. We have an aged C57BL/6 colony.
|Are health reports available?
Yes. Health reports are available for research animal models bred by Charles River in North America.
|Where can I find additional educational resources?
See our expanded digital resources.
|Do you provide information on infectious agents?
Yes. Understanding infectious agents that can contaminate your research animal facility allows you to develop a plan to manage or prevent an outbreak. Our technical sheets contain information on viruses, bacteria/fungi, and parasites prevalent in laboratory animals.
|When can I expect delivery?
Please check with customer service.
|How do I contact Charles River?
Please contact our US client services team directly:
• Email: [email protected]
• Phone: 1-800-522-7287