Charles River & The Jackson Laboratory Seminar 2019

Overview

Hospital Universitari Vall D'hebron

Join us on Thursday, October 31, from 9:45 to 13:30 at Aula 107 del Módulo Norte, Unitat Docent, HUVH, Passeig de la Vall d’Hebron, 119-129, 08035 Barcelona.


Registration is required for this free event. Register today.


Speaker

Dolores Garcia-Arocena, Ph.D.
Senior Technical Information Scientist
The Jackson Laboratory


Agenda, Thursday October 31, 2019

9:45 – 10:00     Registration and Welcome
 

10:00 – 11:00   Genetic Drift – What It Is and How to Minimize Its Impact on Your Research

Over multiple breeding generations, all inbred and genetically modified mouse strains are subject to genetic drift. As a result, the phenotypes associated with the underlying genetic background can also drift. Join us as we discuss the following topics:

  • The basis for genetic drift
  • Case studies demonstrating genetic drift and its effects on experimental results
  • The Jackson Laboratory’s unique, patented Genetic Stability Program (GSP) to stop cumulative genetic drift
  • Steps to ensure the long-term genetic and phenotypic stability of your mouse models


11:00 – 12:00    Cutting Edge Human Disease Modeling Using NSG® Mice

The immunodeficient NOD scid gamma (NSG®) mouse strain enables human disease research that was previously impossible. In this seminar, we will explain how NSG® mice increase the efficiency and sophistication of mouse models of human disease in many important therapeutic areas. Join us as we discuss using NSG® mice to:

  • Create in vivo models which support the growth and integrity of the widest range of human cells and tissues
  • Perform the most efficient and reliable engraftment of human hematopoietic cells to date ("humanization")


12:00 – 12:30     Refreshment Break


12:30 – 13:30     Achieving Reproducible Mouse Studies

Success in the drug development pipeline depends on the success of basic and preclinical research. During this seminar, we will discuss unique experimental design considerations for mouse-based research. Join us to learn about topics important to the reproducibility of your mouse studies such as:

  • Appropriate model and control selection
  • Suitability of phenotypic readout
  • Sample size planning


Contact

Josep Ferrer, Account Manager
Charles River
Mobile: +34 639 615 616
j[email protected]