Charles River Virtual Seminar

RESAL - Lemanic Animal Facility Network

Friday, December 10, 2021 | 09h00 – 12h00


This virtual event will be held on Microsoft Teams.

A few days after registering, you’ll receive an Outlook Calendar invitation to join the presentation.


9h00           Scientific Reproducibility, Biosecurity And The 3rs – Determining How To Acquire Animal Models

The COVID-19 pandemic and its resulting implications have made research institutions think about how to best manage their animal colonies. For both researchers and facility teams, two common questions have arisen – when does it make sense to breed models in-house, and when is it best to obtain them from a qualified vendor? Find out the answers to these questions in this seminar, where you’ll learn about:

  • Reproducibility, breeding, and genetic integrity
  • Best practices for biosecurity and animal health
  • Generating the right number of animals and the 3Rs
  • Opportunity costs and the best utilization of resources
  • Submitting publications and the ARRIVE Guidelines 2.0


10h30          To CRISPR or Not to CRISPR, That Is the Question: IP, Technical Issues & the 3Rs
The use of CRISPR/Cas9* genome editing for the creation of unique rodent models of human disease has revolutionized the field - but every revolution raises challenging issues. View our presentation as we review the latest considerations for the technology as it applies to in vivo research and answer key questions including:

  • CRISPR/Cas9 IP/license constraints: how does it impact your project?
  • Is it compatible with the goals of the 3Rs?
  • Does CRISPR allow for the generation of relevant models?

Jean Cozzi, PhD
Innovation Manager, Genetically Engineered Models and Services Europe
Charles River 


Corinne Schaffner
Business Development Manager
Charles River
P: + 33 6 77 67 03 38
[email protected] 

*CRISPR/CAS9 used under licenses to granted and pending US and international patents from The Broad Institute and ERS Genomics Limited.