Charles River Virtual Seminar

Georg-Speyer-Haus, Frankfurt

Wednesday, 10 March, 13:00 – 15:00


Please register before Monday, 8 March. After you have registered, you will receive an invitation and link via e-mail.


13:00 – 14:00       Proper Management of Transgenic Mouse Colonies – Standardisation and Monitoring

Breeding animal models is far more than simply putting "a male and a female together and hoping for the best." Laboratory animals are used as "biological sensors" and are thereby essential for the reproducibility of scientific results in research. This presentation will cover the following topics to successfully manage your transgenic colonies:

  • How to overcome a crisis involving reproducibility and genetic drift
  • Standardized laboratory animals (biosecurity, housing, breeding)
  • Finding and selecting available mouse models with the right background
  • Technologies to create genetically modified mouse and rat lines
  • Background strain characterization
  • Cryopreservation
  • Refreshing a colony

14:00 – 14:05       Break

14:05 – 15:05       Maintaining a Static Microbiome Across Research Projects: Can It Be Done?

As recent studies have demonstrated, microbiota are key biologic contributors to many aspects of mammalian physiology and behavior; therefore, their influence on research model phenotypes (and subsequent impact on study results) can be considerable.

Join us for this presentation and get the answers to these questions posed by many in the biomedical science community:

  • How can we define and create the precise microbiome consortium researchers need?
  • Once they are created, how can we avoid contamination, or "microbial drift"?
  • What can be done to monitor germ-free animals and those with a customized flora?


Urte Jäh (Dipl. Biol.) 
EU Scientific Service Support Manager
Charles River


Moritz Tacke
Business Development Manager
Charles River 
Mobile: +49 (0) 172 564 34 57
[email protected]