Nutraceuticals and Dietary Supplements

Charles River provides the most accurate, cost-effective, and timely results to support testing raw materials, the production environment, and finished nutraceuticals and dietary supplements.

Dietary Supplements

You can depend on our scientific expertise in microbial identification and strain typing services to support your quality management programs.

Monitor your facility and products against bacterial contamination.

Data gathered from a well-designed and executed environmental monitoring (EM) program provide critical information for tracking and trending on a routine basis. Accurate and consistent species-level identifications result in more confidence in the control of your environment.

Microbial Identification Products & Services

Our AccuGENX-ST® sequence typing allows for comparison below the species level and verification of your probiotic.

It can be used for verification of strains for the microbes used in your products. The resulting DNA sequences, or sequence types, are compared to others in a database and the relationships displayed in a phylogenetic tree. The foundation is built upon DNA sequencing results. SLST/MLST data serve as primary resources for tracking and documenting the genetic relationship of bacteria at a global scale. Results are easily cataloged and referenced for future comparisons. These techniques are highly reproducible, unambiguous and scalable.

Our protocols are designed to meet needed regulatory requirements.

Charles River is ready to help you with your toxicology testing needs. Our exceptional team of scientists regularly design and perform safety programs ranging from acute through chronic toxicity and carcinogenicity studies, and we offer a broad range of animal models and numerous routes of administration.

Toxicology Studies Products & Services

Formulation development services range from preformulation investigations to analytical method development and validation. We prepare formulations based on our extensive knowledge of vehicle suitability in animal models.

Formulation Development

  • pH solubility profiling assessments
  • Dose suitability
  • Compatibility
  • Bioavailability enhancement

Analytical Chemistry

  • High performance liquid chromatography (HPLC)
  • Ultra-high performance liquid chromatography (UPLC)
  • Gas chromatography (GC)
  • Liquid chromatography/mass spectrometry (LC-MS and LC-MS/MS)
  • Atomic absorption spectroscopy (AAS)
  • ICP-OES
  • UV/Vis spectroscopy
  • Fourier transform infrared (FTIR) spectroscopy
  • Capillary electrophoresis (CE)
  • Karl Fischer