Orthopedics Models Medical Device Resources

The Charles River orthopedics and biomaterials team can assist you in the planning and development of both short and long-term animal studies that are fully compliant with regulatory requirements regarding the safety and efficacy evaluation of orthopedic devices. Explore our scientific posters and publications for bone fracture, defect repair, spinal fusion models and more.


Fill out the form to the right to download these orthopedics models medical device resources

Bone fracture and defect repair models publications:

  • Enhanced bioactivity and osseointegration of PEEK with accelerated neutral atom beam technology
  • Efficacy of silicate-substituted calcium phosphate with enhanced strut porosity as a standalone bone graft substitute and autograft extender in an large animal distal femoral critical defect model

Spinal fusion and non-fusion models posters:

  • Novel accelerated neutral atom beam processing as a PEEK surface treatment: a four-month preliminary study using a large animal lumbar intervertebral spinal fusion model
  • Evaluation of bone substitutes using a rabbit posterolateral lumbar intertransverse process spinal fusion (PLF) model: a subchronic pilot study

Joint/cartilage models publication:

  • Tissue healing following segmental meniscal allograft transplantation: a pilot study

Osteoinduction poster:

  • Osseointegration and biocompatibility evaluation of silicon nitride composite using large animal distal femoral epiphyseal insertion and rabbit paravertebral muscle implantation models

Craniomaxillofacial device posters and publications:

  • Safety and efficacy of a novel, gradually anodized dental implant surface: A study in Yucatan minipigs
  • Open-porous scaffolds made of short magnesium fibers as bone defect fillers
  • Fracture healing and bone remodeling with human standard-sized magnesium versus polylactide-co-glycolide (PLGA) plate and screw systems using a mini-swine craniomaxillofacial osteotomy fixation model