Charles River was proud to support the 2020 SPS Virtual Meeting and SPS Virtual Networking Event. In case you missed us at our virtual booth or want to view our posters, online copies and on-demand recordings are now available for download. Please let us know if you have any lingering questions regarding the event.
We provide an extensive, global, and harmonized program to meet the ICH S7A core battery and supplementary safety tests that may be needed based on early observations or concerns, including ICH S7B tests, hERG, and related early safety screening. Our multidisciplinary scientific expertise allows for real-time communication throughout various points in your safety pharmacology evaluations to bridge in vitro and in vivo studies and ultimately meet your timelines and regulatory requirements.
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Spontaneous Incidence of Infrequent Neurological Clinical Signs across Species: A Retrospective Analysis | Simon Authier, Senior Director, Scientific Operations and Veterinary Science |
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Drug-induced Seizures: Considerations for the Underlying Molecular Mechanisms | Mike Accardi, Associate Director, Safety Pharmacology |
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A Comparison of Multiple Left Ventricular Pressure Endpoints as a Screening Tool in Rats | Jennifer Shaffer, Research Scientist, Pharmacology Discovery Services |
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Neurological Assay Performed on Dorsal Root Ganglion from Non-Human Primate and Rodent Origins | Loïs Miraucourt, Research Scientist, Scientific Operations and Veterinary Science |
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QA Interval Heart Rate Correction: Species Comparison of an Indirect Ventricular Contractility Biomarker | Phoebe Zhong, Research Scientist & Study Director, Safety Pharmacology |
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Visualizing QT Prolongation in the Anesthetized Guinea Pig | R. Brandon Borders, Research Scientist, Pharmacology Discovery Services |
A Retrospective Analysis of the Spontaneous Incidence of Neurological Clinical Signs across Species | Simon Authier, Senior Director, Scientific Operations and Veterinary Science
The Underlying Molecular Mechanisms of Drug-Induced Seizures | Mike Accardi, Associate Director, Safety Pharmacology
A Comparison of Multiple Left Ventricular Pressure Endpoints as a Screening Tool in Rats | Jennifer Shaffer, Research Scientist, Pharmacology Discovery Services
Neuroelectrophysiology Assays Performed on Dorsal Root Ganglion from Non-Human Primate and Rodent Origins | Loïs Miraucourt, Research Scientist, Scientific Operations and Veterinary Science
Download our SPS posters and virtual presentations.
Related Resources
- Investigational New Drug (IND) Development Programs Technical Sheet
- Safety Assessment Services Overview
- Safety Pharmacology Services Overview
- The Comprehensive In Vitro Proarrhythmia Assay (CiPA) Guide
- In Vitro Facilities & Capabilities Information (EU)
- Key Considerations to a Successful Safety Pharmacology Integrated Toxicology Study
- CNS Video Resources
- In Vitro and Ex Vivo Neuroelectrophysiology
CNS Assessments from Ex Vivo to In Vitro
Learn more about our CNS Safety Assessments and see how our scientists can help support your drug development with acurate evaluation and identification of potential risks.