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Q: What Breakthrough Technologies Have Had a Transformative Effect on Your Business in 2019?

a lab technician uses a pipette to deposit liquid into test tubes

Pharma's Almanac

In 2019, Charles River announced a strategic partnership with Atomwise, bringing their unique, structure-based artificial intelligence (AI) technology, based on convolutional neural networks for hit identification and optimization, to our partner projects.

The power of this technology is an exciting step forward for Charles River into the AI arena, as it opens up the opportunity to predict binding to protein targets for vast numbers of compounds, including synthesis-on-demand libraries, within a matter of days. Access to such large regions of chemical space becomes very important for those protein targets that are traditionally considered challenging for hit finding and highly competitive "hot targets" where access to novel chemical space is highly desired.

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