Webinar: Chemical CRISPR: A Targeted Protein Degradation Success Story
In this webinar, biology and chemistry leads for the CHDI HDAC4 inhibitor project will share how they successfully handled multiple difficult and atypical targets with a “chemical CRISPR” protein degradation approach.
Webinar: When Biology and Chemistry Collide: A Formula for HTS Success
Join a chemist and a biologist as they work together and teach you how to build a comprehensive screening cascade to ensure translation and HTS success in this webinar.
Webinar: A Molecular Journey to Investigate Memory Enhancement
Through a case study of ONO-8590580, you’ll discover strategies to take a metabolically unstable hit compound through lead optimization, improving functional selectivity, absorption, distribution, metabolism, and excretion (ADME), pharmacokinetics (PK) and brain receptor occupancy along the way.
Webinar: Virtual screening: Personal Reflections and Future Directions
Learn how to effectively handle three important aspects of virtual screening approaches, and avoid pitfalls. After watching this webinar, you'll be able to achieve improved scoring and binding affinity prediction; more reliable ligand preparation; and better handling of protein flexibility, water molecules, and metal ions.
Webinar: Designing a Drug for COVID-19: Considerations for Inhaled Therapeutics to Treat Respiratory Diseases
The lungs are the primary organ affected by COVID-19 and effective respiratory therapies are urgently needed to treat patients suffering from the disease. There are many advantages to delivering a therapeutic directly to the lungs, but designing a drug for inhaled delivery is tricky. Watch this presentation to learn more about designing drugs for inhaled delivery.