Neuroscience 2021

DATE

Week 1: Virtual - November 8-11, 2021

LOCATION

Virtual

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Accelerate your program with new tools and a collaborative, integrated approach that fuels the transition from in vitro biology right into the clinic. Our partnership provides the support you need to conquer the most challenging obstacles of your neuroscience drug discovery programs and accelerate your time to market.

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This year for the Society for Neuroscience (SfN) annual meeting, we decided to look to the future. We took as our basis a timeline created by SfN for their 50th anniversary, and invited experts in their fields to comment on the milestones projected on the timeline.

 

Virtual Panel Discussion: Human Translational Neuroscience

For the last 15 years, the World Health Organization (WHO) has pinpointed brain disorders as ‘one of the greatest threats to public health’ with one in four people affected by neurological or mental health conditions at some point in their lives. While there is currently a host of treatments for these disorders, there are no cures. Translational neuroscience aims to resolve this by transforming knowledge gained from basic science into interventions and applications for treating human disease. In the absence of a “perfect,” model, some approaches combine existing animal models and human induced pluripotent stem cell models to increase the translatability of results. To understand why past decades of research have failed to result in successful treatments, we must understand the impact of human translational neuroscience research.

Register to join the panel discussion as renowned neuroscience pioneers dissect approaches from the following two distinct modalities: animal to human and stem cell to human translational models.

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Moderator

 

Headshot of Toni Ahtoniemi.

 

Toni Ahtoniemi, PhD

Associate Director, Client Services at Charles River

Read Toni’s bio and publications

 

 

Panelists

 

Headshot of Lowry Curley.

 

Lowry Curley

Chief Executive Officer at AxoSim Inc. 

 

 


Headshot of mark kotter.

 

Mark Kotter

Founder and CEO of Bit Bio

 

 


Headshot of Simon Authier.

 

Simon Authier

Senior Director of Scientific Operations and Veterinary Science

 

 

 

Check out our posters at this year's SfN annual meeting:

Cognition: Animal Models of Schizophrenia

Poster #4619: Roluperidone (MIN-101) Causes Brain Region-Specific Neurotransmitter Release, Increased Brain Activity and Functional Network Connectivity in the Rat Brain Related to Negative Symptoms in Schizophrenia
Takeda in Collaboration With Charles River

Huntington's Disease: Models

Poster #5557: Evaluation of marmoset as possible non-human primate model for HTT splicing modulation studies
Maria Herva Moyano, Charles River

Poster #3529: Next generation reprogramming of human iPSCs to generate disease-specific glutamatergic neurons carrying HTT gene for Huntington’s disease research and drug discovery
Mariangela Iovino, Charles River

Huntington's Disease: Preclinical Interventions

Poster #679: Evaluation of a small molecule splicing modulator in a humanized HTT intron 49 mouse
Dario Magnani, Charles River

Poster #692: Profiling of a novel orally active and brain penetrant splicing modulator small molecule demonstrates CNS and systemic mHTT lowering in BACHD mice
Maria Herva Moyano, Charles River

Motor Neuron Disease: Therapeutics

Poster #3257: High-throughput screening (HTS) for identification of a tool compound targeting the interaction of SRSF1 with C9orf72 to prevent nuclear export in ALS and FTD
Rhea van de Bospoort, Charles River

Single-Cell Techniques II

Poster #3197: Huntingtons disease (HD) human embryonic stem cells (hESCs) with mono-allelic HTT exon 12 genomic barcoding show applicable pharmacological responses, retain relevant neuronal differentiation capacity and demonstrate allele selectivity screening potential
Charles River in Collaboration With CHDI

Voltage-Gated Sodium Channels

Poster #1031: Identifying Novel and Selective Sodium Channel Modulators from Theraphosidae Venoms
Juha Kammonen, Charles River

Empower your program with insights from our team – browse our collection of neuroscience resources.

 

Browse All Neuroscience Resources

 

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Viral Vector Resources

Learn more about our many neuroscience research tools, including viral vectors, biosensors, and Parkinson’s Disease tools.

Browse The Resources

 

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The Webinar Collection

Learn more about our neuroscience portfolio by watching our webinar series.

Browse the Webinars

 

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Neuroscience In Vitro Services: A Virtual Tour

Our collection of neuroscience-focused in vitro services are highlighted in this all-encompassing virtual tour of our facilities.

Watch the Video