Preclinical Medical Device Testing

Preclinical Medical Device Testing

Safety and Efficacy Models from a Dedicated Medical Device CRO

Charles River’s two state-of-the-art facilities in North America fully support your medical device testing programs. Our comprehensive portfolio of services includes imaging modalities and diverse histological endpoints that are quantitatively assessed using manual and software-guided automated histomorphometry. Our staff features dedicated veterinary pathologists who can perform a full histopathological analysis and create resulting quantitative reports.

 

Antisense Oligonucleotide Therapy Screening

Antisense Oligonucleotide Therapy Screening

Screening Services for ASO Gene Therapy

Antisense oligonucleotide therapy uses single-stranded oligonucleotides that can alter RNA expression and splicing and thereby reduce, restore, or modify protein expression in personalized ASO gene therapy. Screening assays are designed to measure the results of distinct mechanisms of action, such as RNaseH recruitment, splicing modification, and miRNA targeting. Thorough ASO profiling ensures efficient binding and effective modulation to predict successful personalized antisense therapy.

2020 Charles River Microbial Solutions Calendar

 Insourcing Solutions℠ for Commercial Organizations

 Insourcing Solutions℠ for Commercial Organizations

How We Can Help Pharmaceutical and Biotech Companies

Our programs can be customized to not only fill technical, veterinary, or scientific gaps within your institution, but to also have the capability to expand your research and development reach through outsourced turnkey vivarium options.

 Insourcing Solutions℠ for Academia

 Insourcing Solutions℠ for Academia

How We Can Help Academic Institutions

Academic institutions often require additional support for their existing laboratory animal resources (LAR) program. As research and technology is ever-changing, the needs of each investigator change as well. Charles River Insourcing Solutions℠ offers a customizable workplace solution that allows you fill the gaps and meet the current needs of your facility.

 Insourcing Solutions℠ for Government

 Insourcing Solutions℠ for Government

 How We Can Help the Government Sector

Charles River's extensive experience and long-standing association with the US National Institute of Health (NIH) and various Institutes and Centers (ICs) around the world allows us to provide prompt, efficient, and high-quality scientific staffing in the form of veterinary, technical, animal care, and administrative professionals.

Neuroinflammation Studies

Neuroinflammation Studies

Neuroinflammatory Disorders

Neuroinflammatory disorders are the chronic inflammation of the central nervous system. It may be the result of an acute event like traumatic brain injury or a viral infection.

Science Day: Beyond the Small Molecule

Science Day: Beyond the Small Molecule

Recently, we held a scientific exchange to celebrate another year of the Charles River and AstraZeneca strategic partnership. As the industry evolves and changes, our groups strive to stay ahead of these challenges and to set the industry standard in accelerating drugs to market. We would like to thank you for joining us for a day of joint presentations, posters, and collaborations with your counterparts. Click the links below to download the presentations from the Science Day. 

Inbred Mice

Charles River Presents: The Neuroinflammation Symposium

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