Gastric Cell Line: MKN-45

• Internal Xenograft Data
• XL888, a Novel, Synthetic, Orally Bioavailable Inhibitor of HSP90
• CDX2 does not suppress tumorigenicity in the human gastric cancer cell line MKN45

NU/NU Nude Mouse

• Sonic Hedgehog Pathway Is Essential for Maintenance of Cancer Stem-Like Cells in Human Gastric Cancer
• Role of Gastrointestinal Hormones in the Proliferation of Normal and Neoplastic Tissues

Fox Chase SCID Mouse (C.B.17 SCID)

• Adenovirus-mediated Transfection of Caspase-8 Augments Anoikis and Inhibits Peritoneal Dissemination of Human Gastric Carcinoma Cells

BALB/c  Nude Mouse

• In vitro and in vivo anti-tumour effects of a humanised monoclonal antibody against c-erbB-2 product