Leukemia/Lymphoma Cell Line: Daudi

• CAT-8015: A Second-generation Pseudomonas Exotoxin A-Based Immunotherapy Targeting CD22 -Expressing Hematological Malignancies

NU/NU Nude Mouse

• Single-Chain Fv-Streptavidin Substantially Improved Therapeutic Index in Multistep Targeting Directed at Disialoganglioside GD
• Selective killing of Burkitt’s lymphoma cells by mBAFF-targeted delivery of PinX1 

Fox Chase SCID Mouse (C.B.17 SCID)

• Internal Xenograft Data
• Interleukin 4 Retards Dissemination of a Human B-Cell Lymphoma in Severe Combined Immunodeficient Mice

Fox Chase SCID Beige Mouse

• Antitumor Activity of Fab' and IgG-anti-CD22 Immunotoxins in Disseminated Human B Lymphoma Grown in Mice with Severe Combined Immunodeficiency Disease: Effect on Tumor Cells in Extranodal Sites
• Selective killing of Burkitt’s lymphoma cells by mBAFF-targeted delivery of PinX1
• Single-Chain Fv-Streptavidin Substantially Improved Therapeutic Index in Multistep Targeting Directed at Disialoganglioside GD2

BALB/c Nude Mouse

• CD32B, the human inhibitory Fc-γ receptor IIB, as a target for monoclonal antibody therapy of B-cell lymphoma

CD-1 Nude Mouse

• Experimental tumoricidal effects of monoclonal antibody against solid breast tumors