Leukemia/Lymphoma Cell Line: K-562

• Lack of Correlation between Natural Killer Activity and Tumor Growth Control in Nude Mice with Different Immune Defects
• Development of Myelosarcomas from Human Myelogenous Leukemia Cells Transplanted in Athymic Mice
• COX-2 independent induction of apoptosis by etodolac in leukemia cells in vitro and growth inhibition of leukemia cells in vivo

NU/NU Nude Mouse

• A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma
• Two New Monoclonal Antibodies, Lym-1 and Lym-2, Reactive with Human B-Lymphocytes and Derived Tumors, with Immunodiagnostic and Immunotherapeutic Potential
• A new human acute monocytic leukemia cell line SHI-1 with t(6;11)(q27;q23), p53 gene alterations and high tumorigenicity in nude mice

Fox Chase SCID Mouse (C.B.17 SCID)

• Internal Xenograft Data
• Stressed apoptotic tumor cells express heat shock proteins and elicit tumor-specific immunity
• Antileukemia activity of a natural killer cell line against human leukemias.

Fox Chase SCID Beige Mouse

• Evaluation of ex vivo expanded human NK cells on antileukemia activity in SCID-beige mice
• The Heat Shock Protein HSP70 Promotes Mouse NK Cell Activity against Tumors That Express Inducible NKG2D Ligands
• Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome–positive leukemia