Multiple Myeloma Cell Line: OPM2

• Tissue inhibitor of metalloproteinase 1 (TIMP-1) promotes plasmablastic differentiation of a Burkitt lymphoma cell line: implications in the pathogenesis of plasmacytic/plasmablastic tumors
• Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma

NU/NU Nude Mouse

• Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice

Fox Chase SCID Mouse (C.B.17 SCID)

• Internal Xenograft Data
• Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice
• In Vitro and in Vivo Activity of the Maytansinoid Immunoconjugate huN901-N^2′- Deacetyl- N^2′-(3 Mercapto-1-Oxopropyl)-Maytansine against CD56⁺ Multiple Myeloma Cells