Athymic Nude Mouse Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition NU/NU Nude Mouse Notch signaling contributes to the pathogenesis of human osteosarcomas A fully human insulin-like growth factor-I receptor Antibody SCH 717454 (Robatumumab) has antitumor activity as a single agent and in combination with cytotoxics in pediatric tumor xenografts Fox Chase SCID Mouse (C.B.17 SCID) Immunotherapy for Osteosarcoma: Genetic Modification of T cells Overcomes Low Levels of Tumor Antigen Expression Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways Impact of integrin αvß3 expression and activation on osteosarcoma metastasis
