Click on each resource below to learn more about how scientific advisory services from Charles River can help support your study.
-
Whitepapers
Need to Accelerate Drug Development?
All drug R&D is expensive, but the cost and time lost from backtracking can significantly impact preclinical costs and set your IND start back a year or more. This whitepaper discusses how you can insure your program against these losses by enlisting help from experienced Charles River Scientific Advisors.
Download the Whitepaper -
Webinars
A Blueprint for Translational Integrated Drug Discovery
What does the future of your drug discovery program look like? Many industry leaders are finding themselves in uncharted waters: the science is more sophisticated than ever, producing paradigm-altering treatments. This webinar will cover how to optimize your operations and build a new model for drug development that emphasizes collaboration and novel approaches to funding.
Watch the WebinarConsiderations for Moving Your Program from Discovery to Safety: A Case Study
This presentation will provide insight into the drug discovery process within the pharmaceutical and biotech environments with a focus on the importance of target engagement biomarkers and the role they can play from a translational efficacy and side effect liability perspective. An integrated project case study will provide context as well as illustrate how Charles River’s multidisciplinary project teams transition projects for their partners seamlessly through discovery into GLP safety and toxicology studies.
Watch the WebinarHow to Design & Execute Successful CAR T Cell Therapy Programs (Available in The Source℠)
In recent years there has been unprecedented progress in the development of new cellular therapies for cancer culminating in the first FDA approvals of Chimeric Antigen Receptors or CAR T cellular therapies. In this webinar you will learn how to move your CAR T cellular therapy program successfully and rapidly to market.
Watch the WebinarHow to Design a Scientifically Robust Preclinical Program for Biological Therapeutics
This webinar addresses preclinical program designs for biological therapeutics. Using case studies, our speakers explore key areas to consider when building these complicated safety assessment packages in accordance with regulatory guidance and the 3Rs.
Watch the WebinarNonclinical Safety Evaluation of Preventive Vaccines
In this webinar, you’ll learn how to design appropriate toxicity tests for vaccines and new adjuvants and how to determine most relevant animal models for your vaccine’s safety program.
Watch the Webinar -
Blogs
Antisense Therapies and Angelman Syndrome
The chances of finding a cure for Angelman Syndrome, a rare genetic disorder are looking better and better.
Read the BlogCommon Hiccups in Safety Assessment
When trying to turn inventions into drugs, who you partner with matters. Four things that can slow down drug development.
Read the BlogEvolve or Go Extinct
How and why the CRO industry must adapt to survive a changing drug development universe.
Read the BlogHow Predictive Toxicology is Influencing Regulatory Approaches
New non-animal models and a weight of evidence approach could reduce the amount of animal testing required by regulators.
Read the BlogSafety Assessment with Antisense Oligonucleotides
The past influences the present……. and the future holds great promise.
Read the Blog -
Video
Tackling Program Challenges in Cellular Therapy Research and Development
The complexities of cellular therapy programs present scientific and technical challenges. They are highly customized and vary greatly based on product attributes.
Watch the VideoDrug Discovery Chemists Play a Major Role in Hit Identification
Our computational chemists work closely with medicinal chemists and can play a major role in hit identification through the application of both structure and ligand-based screening. With 340 patents and two decades of experience, Charles River’s medicinal chemistry team is ready to help.
Watch the Video -
Tools
Biomarker Database
Our Biomarker Database contains over 4500 available markers.
Learn MoreTest Article Calculator
Have a product that requires safety evaluation? You’re going to need to know how much to supply your toxicology partner for dosing* your studies, and our interactive calculator can help.
Learn MoreCancer Model Database
Charles River has developed an online Compendium of our tumor models that allows you to search by the features that interest you. You can find the model you need by searching for a specific histology or molecular property.
Learn MoreWhich Oncology Models Are Right For Me?
Answer a few brief questions about your program to receive expert guidance on the most appropriate models for your program.
Learn More -
Articles
Guidelines in Toxicology: A Blessing and a Curse
A look at the evolution of drug development regulatory guides.
Read the Article