Overview

Charles River offers an expert panel of services for the characterization of glycosylation. We specialize in comparability programs that may be used for manufacturing/process changes and for comparisons of originator vs. biosimilar products.

  • Glycosylation Site Occupancy and Mapping via Peptide Mapping LC-MS/MS
  • N-Linked Oligosaccharide Profile via LC-MS/MS
  • O-Linked Oligosaccharide Profile via LC-MS/MS
  • Quantitative Monosaccharide Analysis
  • Quantitative Sialic Acid Determination
  • Glycan Structural Characterization / Confirmation via MSn
  • Glycan Profile / Isoform via cIEF
  • Exoglycosidase Glycan Sequence / Mapping

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