Monoclonal & Polyclonal Antisera Production Services

Charles River offers monoclonal and polyclonal antisera production in a variety of species, such as rodents and farm animals. Projects can be customized to client-specific requirements and cGMP standards. Options include production of antisera by Charles River or preparation of animals for production and shipment to client. Routes of injection are dependent on species of animal used but include: ID, SC, IM, IV, and IP. Subcontracting for purification of antisera is also available.

In addition to antisera, we can also provide:

  • Defibrinated blood products
  • Whole blood in anticoagulant (sodium citrate, Alsever’s, heparin)
  • Serum
  • Plasma
  • Lysed blood

Monoclonal Antibodies

Charles River develops and produces monoclonal antibodies (in vitro production of hybridomas) in collaboration with a subcontractor. We offer our standard services or customized development and production services based on client needs.

Polyclonal Antibodies

Charles River offers polyclonal antibody production on different species (rabbits, rodents, guinea pigs, sheep) and related support services, such as antigen synthesis and antibody purification and labeling, in collaboration with a subcontractor.