Compound Solubility, Dissolution and Stability Services

Pharmaceutical scientists at Charles River can measure the solubility, dissolution and stability of compounds under a variety of conditions. We leverage our expertise and experience to de-risk candidate molecules with respect to their pharmaceutical developability. Charles River clients successfully gain insight on major liabilities at a stage when they can be easily addressed.

Question for our chemists?

Charles River supports client pharmaceutical sciences and formulation programs in these ways:

  • Kinetic solubility measurement
  • Thermodynamic solubility measurement
  • pH solubility measurement
  • Solubility/Stability measurements in lung, gastric and intestinal fluid mimetics
  • Preliminary small scale dissolution testing