Target Discovery Services

We examine the effects of introducing shRNAs (SilenceSelect®) or full-length cDNAs (FLeXSelect®) contained within our libraries of adenoviruses into human primary cells, differentiated stem cells or cell lines. siRNA and miRNA technologies are also available for gene knockdown studies. Advanced readouts, such as high-content screening and high-throughput gene expression analysis, are used to measure the effects of knockdown and thus identify the genes that have an effect on a disease-relevant pathway.

Capabilities


Integrated Drug Discovery Seminar Series

Attend the seminar to learn how Charles River’s integrated drug discovery programs have reduced this timeline through industry experienced, multi-disciplinary teams focused on resource efficiency, scientific excellence and strategic partnerships with clients through all aspects of drug discovery.

Charles River chemistry and biology leaders host seminars throughout the year to share data and present case studies on how to optimize the drug discovery workflow.

Check for a location near you