In Vitro Models & Assays to In Vivo Pharmacology
Translation from in vitro models & assays into animal models are critical to understanding the progression of neurological disease while providing a complete interactive physiology to understand the pharmacokinetics and pharmacodynamics of a candidate. We have developed robust and reproducible in vitro models and in vivo pharmacology studies that are validated for multiple assay platforms and reliable tools to screen small molecules to biologics.
Disease Areas
Translational Tools for Neuroscience Discovery
Phenotypic assays using various neuronal cellular and animal models are robust tools to discover new disease targets, perform high throughput screens, understand mechanism of action, and develop clinically relevant biomarkers. Our comprehensive suite of imaging and electrophysiology modalities, behavioral and other biomarker methods and endpoints enable more effective decision-making to help move your research forward.
Neuroscience Resources
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TECHNICAL SHEETS
Models, Services & Tools
- Neuroscience Drug Discovery Overview
- Portfolio of Validated Neurological Disease Animal Models
- Preclinical Imaging Capabilities for Neurological Diseases
- Translational Tools for Neuroscience Drug Discovery
Neuroscience Facilities
- South San Francisco, California, Facility At-a-Glance
- Kuopio, Finland, Facility At-a-Glance
- Cambridge, UK, Facility Overview
- Portishead, UK Facility Overview
- Leiden, Netherlands Facility Overview
Ion Channel Screening Services
- Ion Channel Selectivity Profiling: Neurodegeneration/Stroke
- Ion Channel Selectivity Profiling: Pain/Inflammation
- Ion Channel Selectivity Profiling:Psychiatric Disorder
- Ion Channel Selectivity Profiling: Seizure/Convulsion
Off-the-shelf Assays
- SCIENTIFIC POSTERS
- VIDEOS