In Vitro Models & Assays to In Vivo Pharmacology

Translation from in vitro models & assays into animal models are critical to understanding the progression of neurological disease while providing a complete interactive physiology to understand the pharmacokinetics and pharmacodynamics of a candidate. We have developed robust and reproducible in vitro models and in vivo pharmacology studies that are validated for multiple assay platforms and reliable tools to screen small molecules to biologics.

The Disruptors: Conversations in Science

To pay homage to the most disruptive and visionary scientists leading the effort on the frontlines, Charles River is sharing stories about the state and direction of scientific research, discovery, and therapeutic development.
Meet the Disruptors

Disease Areas

Translational Tools for Neuroscience Discovery

Phenotypic assays using various neuronal cellular and animal models are robust tools to discover new disease targets, perform high throughput screens, understand mechanism of action, and develop clinically relevant biomarkers. Our comprehensive suite of imaging and electrophysiology modalities, behavioral and other biomarker methods and endpoints enable more effective decision-making to help move your research forward.

Neuroscience Resources