Neuroscience Animal Models and Services

Rodent to large animal species are typically used to test lead candidate compounds in the later stages of preclinical testing. Charles River has acquired new capabilities to validate various animal models of neurological disease, including multiple sclerosis, Parkinson’s disease, and Alzheimer’s disease. Biological modalities, small molecules, and gene therapy can be tested in all of these animal models.

ASK US HOW WE CAN SUPPORT YOUR CANDIDATE TESTING

Our services include:

  • Microdialysis (test compound [including antibodies], neurotransmitters, and peptides)
  • Pharmacokinetics and pharmcodynamics in CSF, plasma, dialysate, and tissues
  • Cognitive testing using touchscreen technology
  • EEG
  • MRI-guided injection of gene therapies