MetaQuant Probes
Our MetaQuant probe provides truly quantitative dialysis, which saves time and money in the process. Typically, free-drug concentrations in tissue are calculated by measuring the total drug concentration, then subtracting the bound-drug, based on an in vitro protein binding calculation. Our proprietary MetaQuant probe allows for accurate measurement of actual free-drug concentrations, vs. inferred concentration based on standard calculations.
Advantages include:
- No more anomalies between in vitro and in vivo data
- Fewer animals required for testing
- Fast turnover without extensive validation required
- Ability to track over time from the same animal, and in combination with other techniques