Overview

Our integrated approach allows the comprehensive evaluation of bone and cartilage drug efficacy, musculoskeletal tissue healing and biocompatibility, orthopedic device efficacy and the effects of new orthobiologic applications.

Models

  • Gonadectomy (ovariectomy and orchiectomy)-induced bone loss for osteoporosis drug testing
  • 5/6 nephrectomy model
  • TPTx (thyroparathyroidectomy) model
  • Schenk model in weanling rats (screen for anti-resorptive agents)
  • Bone defect models
  • Orthopedic models
  • Osteoarthritis models
  • Rheumatoid arthritis models

Note: Non-GLP efficacy models are also available for your early research.

Support Services

  • Imaging using bone densitometry techniques
  • Biochemical markers of bone and cartilage turnover
  • Radiographic diagnostics (X-ray)
  • Histomorphometry and histology
  • Biomechanical strength testing
  • Micro-CT scanning