Oncology Drug Discovery

Charles River’s experience with oncology drug discovery spans all phases, from target identification to IND studies. Utilizing the most effective combination of tools available to identify promising compounds, we work with our partners to design studies by selecting from amongst a broad range of well-characterized xenograft, patient-derived xenograft (PDX), and syngeneic tumor models. Combining those models with appropriate biomarkers, including flow cytometry and imaging, allows our partners to choose the most appropriate study design and screening method to identify promising compounds and optimize lead candidates.

Charles River can aid oncology drug discovery across a range of modalities including small molecules, immune therapies, biologics, cell therapies, and our BSL2 facilities allow us to work with various viral vectors and cancer vaccines. Each of our models are supported by a range of translational tools including ELISpot, flow cytometry, and imaging.


AACR Posters Now Available

Abstract 3D render of of cancer cells.

Check out our scientific posters from the AACR Annual Meeting 2019 in Atlanta, Georgia.
Download Here


Available Oncology Models/Studies

Charles River Oncology

Image of cancer cells surrounded by healthy cells.In the fast-paced field of oncology research, it can be tough to stay up to date on the latest advancements. Visit our oncology microsite for the latest research in the field and for more information about our services.

Learn More

Charles River’s Oncology Fast 5, is a scientist-curated skim of industry articles, blog posts, data, and interactive content covering hot topics in cancer research. Sign up