Transgenic/knockout model development, large number of unmyelinated axons in lumbar motor roots

Transgenic/knockout model development, large number of unmyelinated axons in lumbar motor roots

Atherosclerotic model, cancer research, metabolic research, diet-induced obesity

Tumor biology and xenograft research

Immunology, inflammation

Creation of chimeras with B6N-derived embryonic stem cells

Safety and efficacy testing, transgenic/knockout model development, transplantation research

Hybrid vigor, as a background for deleterious mutations, to create or enhance expression of polygenic diseases, to determine the mode of inheritance, and to provide physiological buffering (present a broader array of responses to various stresses)

Safety and efficacy testing, transgenic/knockout model development, transplantation research, behavioral research

General multipurpose model, hybridoma development, monoclonal antibody production, infectious disease