C57BL/6J (JAX® Mice Strain)

C57BL/6J
Inbred
C57BL/6J JAX Mouse
Breeding Location

C57BL/6J (JAX® Mice Strain) Details

C57BL/6J is the most widely used inbred strain and the first to have its genome sequenced. Although this strain is refractory to many tumors, it is a permissive background for maximal expression of most mutations. C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss. They are also susceptible to diet-induced obesity, type 2 diabetes, and atherosclerosis. Macrophages from this strain are resistant to the effects of anthrax lethal toxin. It was introduced into The Jackson Laboratory in 1948, at F22, then to Charles River Laboratories France in 1981 and UK in 2004. Breeding is in accordance with The Jackson Laboratory genetic management system.

Note: We also offer aged C57BL/6J mice and C57BL/6J SOPF mice with an SOPF health profile (bred in France and the UK).

 

Coat Color
Black
Strain Code
632
Ideal For
General multipurpose model, diet-induced obesity, transgenic/knockout model development, safety and efficacy testing, immunology

JAX-C57BL_6J%20Germany%20Growth%20Chart.jpg

Growth chart data should be used as a guideline only.
The shaded areas on each chart are the mean weight plus or minus one standard deviation at a given age averaged across all production facilities. This represents approximately 67% of the population, with the remaining 33% falling outside of this weight range.

C57BL/6J (JAX® Mice Strain) Details

C57BL/6J is the most widely used inbred strain and the first to have its genome sequenced. Although this strain is refractory to many tumors, it is a permissive background for maximal expression of most mutations. C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss. They are also susceptible to diet-induced obesity, type 2 diabetes, and atherosclerosis. Macrophages from this strain are resistant to the effects of anthrax lethal toxin. It was introduced into The Jackson Laboratory in 1948, at F22, then to Charles River Laboratories France in 1981 and UK in 2004. Breeding is in accordance with The Jackson Laboratory genetic management system.

Note: We also offer aged C57BL/6J mice and C57BL/6J SOPF mice with an SOPF health profile (bred in France and the UK).

 

Coat Color
Black
Strain Code
632
Ideal For
General multipurpose model, diet-induced obesity, transgenic/knockout model development, safety and efficacy testing, immunology

JAX-C57BL_6J%20UK%20Growth%20Chart.jpg

Growth chart data should be used as a guideline only.
The shaded areas on each chart are the mean weight plus or minus one standard deviation at a given age averaged across all production facilities. This represents approximately 67% of the population, with the remaining 33% falling outside of this weight range.

C57BL/6J (JAX® Mice Strain) Details

C57BL/6J is the most widely used inbred strain and the first to have its genome sequenced. Although this strain is refractory to many tumors, it is a permissive background for maximal expression of most mutations. C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss. They are also susceptible to diet-induced obesity, type 2 diabetes, and atherosclerosis. Macrophages from this strain are resistant to the effects of anthrax lethal toxin. It was introduced into The Jackson Laboratory in 1948, at F22, then to Charles River Laboratories France in 1981 and UK in 2004. Breeding is in accordance with The Jackson Laboratory genetic management system.

Note: We also offer aged C57BL/6J mice and C57BL/6J SOPF mice with an SOPF health profile (bred in France and the UK).

 

Coat Color
Black
Strain Code
632
Ideal For
General multipurpose model, diet-induced obesity, transgenic/knockout model development, safety and efficacy testing, immunology

JAX-C57BL_6J%20France%20Growth%20Chart.jpg

Growth chart data should be used as a guideline only.
The shaded areas on each chart are the mean weight plus or minus one standard deviation at a given age averaged across all production facilities. This represents approximately 67% of the population, with the remaining 33% falling outside of this weight range.
brown mouse

WHITEPAPER
Aged C57BL/6J Mice for Research Studies
Learn about special considerations for maximizing the translational value of data collected from aged mice and tools for implementing best practices.
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JAX® MICE AND RESEARCH SERVICES


Charles River is the exclusive distributor of JAX® Mice and select research services in Europe, Korea, and Taiwan.

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JAX® is a trademark of The Jackson Laboratory registered in the United States. All rights reserved.

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This mouse model is part of the Jackson Laboratory patented Genetic Stability Program (GSP). Only The Jackson Laboratory and Charles River in Europe maintain colonies of JAX® Mice strains which are derived from pedigreed mice from The Jackson Laboratory and are re-infused routinely with pedigreed mice to stabilise the genetic integrity and phenotype of these strains.


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