NCI SCID/NCr Mouse

CB17/Icr-Prkdcscid/IcrCr
Immunodeficient
SCID NCr Mouse
SCID NCr Mouse

NCI SCID/NCr Mouse Details

SCID mice possess a genetic autosomal recessive mutationĀ Prkdcscid. Discovered in 1980 by Bosma in C.B-17/Icr mice at Fox Chase Cancer Center. SCID mice show a severe combined immunodeficiency affecting both B and T lymphocytes. They have normal natural killer (NK) cells, macrophages and granulocytes. NCI received this mouse in 1991. To Charles River in 2014.

Coat Color
White (albino)

Strain Code
561

Ideal For
tumor biology and xenograft research

Bred in