THE POUND MOUSE Details
This model was isolated from a C57BL/6NCrl colony in a Charles River Laboratories barrier facility in the US in 2005. The mutation was mapped to a region within less than 2 cM of the leptin receptor on Chr 4. Lack of leptin receptor protein. Het x Het mating.
Coat Color
Black
Strain Code
This model is cryopreserved.
Ideal For
obesity, hyperinsulinemia, insulin resistance, dyslipidemia, metabolic syndrome, leptin receptor deficiency, fatty liver disease
- THE POUND MOUSE™: A Model for Metabolic Syndrome/Pre-Diabetes
- Animal Models of Metabolic, Renal and Cardiovascular Disease Datasheet
- Comparison of Insulin Levels for the C57BL/6NCrl-Leprdb-lb/Crl (THE POUND MOUSE™) and Other Mouse Models Fed Purina 5008 Diet October 2006
- Comparison of Glucose Levels for the C57BL/6NCrl-Leprdb-lb/Crl (THE POUND MOUSE™) and Other Mouse Models Fed Purina 5008 Diet October 2006
- Comparison of Cholesterol Levels for the C57BL/6NCrl-Leprdb-lb/Crl (THE POUND MOUSE™) and Other Mouse Models Fed Purina 5008 Diet October 2006
- Comparison of Leptin Levels for the C57BL/6NCrl-Leprdb-lb/Crl (THE POUND MOUSE™) and Other Mouse Models Fed Purina 5008 Diet October 2006
- Comparison of Triglyceride Levels for the C57BL/6NCrl-Leprdb-lb/Crl (THE POUND MOUSE™) and Other Mouse Models Fed Purina 5008 Diet October 2006
Technical Resources
Informational Resources: THE POUND MOUSE
Baseline Data