ZDSD rat
Breeding Location

ZDSD Rat Details

The ZDSD rat colony was started by crossing ZDF/GMI rats with Crl:CD rats in 2001 at PreClinOmics, under the direction of Dr. Richard Peterson. The colony was perpetuated by inbreeding selected obese animals from litters that had a tendency for developing diabetes. Selected animals from the colony were rederived in 2009 at 21 generations. The selective inbreeding was continued for a total of 45 generations in this colony until 2016 under the direction of Dr. Peterson when Crown Bioscience purchased PreClinOmics. They continued the inbreeding of the ZDSD rat colony until generation 57 (2018) in the PreClinOmics breeding facilities. To Charles River in 2018 from CrownBio.

Some for-profit entities will require a license from CrownBio to purchase this model. To find out if you need to obtain a license, please contact us at [email protected].

Coat Color
Black-hooded with black stripe down the length of the back

Strain Code

Ideal For
Type 2 diabetes, pre-diabetes, obesity, metabolic syndrome (insulin resistance, dyslipidemia, and hypertension), diabetic complications (nephropathy, neuropathy, fatty liver) Note: The female ZDSD does not develop diabetes. Limited inventory is available.

Not available.

LOCATION: Kingston

Unit: K98

Download the Report