Bioanalysis for Biologics

Peptides, monoclonal antibodies (mAb), multi-domain antibodies, antibody-drug conjugates (ADC), biosimilars, and traditional and next-generation oligonucleotides – Charles River scientists are global leaders in this rapidly growing and evolving field.

Ligand binding assay bioanalysis is not an independent discipline; our scientists work closely with our immunogenicity, pharmacokinetic, and statistical specialists to deliver the pertinent solutions and interpretations applicable to your molecule and your study.

Platforms

  • Ligand binding assays (ELISA and MSD)
  • Automated ELISA systems
  • Ligand binding with LC-MS detection (hybrid assays)
  • LC-MS/MS
  • Oligonucleotides
  • High-resolution mass spectrometry
  • Luminex® technologies
  • Radioimmunoassay (RIA)
  • Enzyme immunoassay (EIA)
  • Fluorescence immunoassay (FIA)
  • Immunoradiometric assay (IRMA)
  • Dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA)
  • Scintillation proximity assay (SPA)
  • Gyrolab