Rapid Endotoxin Detection Solutions

Charles River offers several highly flexible rapid bacterial endotoxin testing platforms to meet the needs of a variety of sample throughput and different lab sizes and configurations. All Endosafe® endotoxin testing solutions support the same FDA-licensed cartridges for accurate, convenient, and real-time endotoxin testing, glucan concentration determination, and Gram identification. In addition, every system integrates with the Charles River Cortex™ data management software platform, creating a robust, optimally controlled endotoxin testing program. Our rapid LAL test methods allow you to produce results right at the point of sample collection, as well as improve sample management, decrease testing time, and accelerate product production. 

Our Endosafe® endotoxin testing equipment and cartridge technology are our innovative solution to our customers’ need for higher sensitivity and quicker quantitative results.

technician using Endosafe nexgen-PTS rapid endotoxin testing equipment Endosafe® nexgen-PTS™: The Endosafe® nexgen-PTS™ is a rapid, point-of-use handheld spectrophotometer that utilizes USP/BET-compliant disposable cartridges for precise, convenient, and real-time endotoxin testing, glucan concentration determination, and Gram identification.



technician using Endosafe nexgen-MCS rapid endotoxin testing equipment Endosafe® nexgen-MCS™: This multi-cartridge benchtop LAL test equipment addresses the need for higher sample throughput while utilizing the same FDA-licensed LAL cartridge technology as the Endosafe® nexgen-PTS. The Endosafe ® nexgen-MCS™ is proficient at concurrently testing up to five samples within 15 minutes for rapid, quantitative, and accurate endotoxin results.


Endosafe Nexus endotoxin testing solution Endosafe® Nexus™: The Endosafe® Nexus™ delivers rapid, quantitative results in a low-maintenance, high-precision package as the first fully automated robotic system which eliminates high-volume testing variables and unlocks the full potential of our Endosafe® cartridge technology.



technician using the BioTek ELX808IU reader endotoxin testing equipment BioTek® Plate Readers: We are able to provide an exceptional level of support for BioTek® endotoxin testing equipment due to our partnership with BioTek ®. In addition to selling the BioTek® ELX808IU™ reader, our technical support department qualifies the instrument for compatibility with Endoscan-V™ software and the LAL test.


Horseshoe Crabs used for LAL production for endotoxin testing injectable pharmaceutical products and medical devices

Vital Science S2, E08: The Life (Saving) Blood of Horseshoe Crabs

Our panel explores the vital role horseshoe crabs play in bacterial endotoxin testing and the ongoing battle to preserve the population.

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Frequently Asked Questions (FAQs) on Endotoxin Testing Equipment