Rapid Endotoxin Detection Solutions
Charles River offers several highly flexible rapid bacterial endotoxin testing platforms to meet the needs of a variety of sample throughput and different lab sizes and configurations. All Endosafe® endotoxin testing solutions support the same FDA-licensed cartridges for accurate, convenient, and real-time endotoxin testing, glucan concentration determination, and Gram identification. In addition, every system integrates with the Charles River Cortex™ data management software platform, creating a robust, optimally controlled endotoxin testing program. Our rapid LAL test methods allow you to produce results right at the point of sample collection, as well as improve sample management, decrease testing time, and accelerate product production.
Our Endosafe® endotoxin testing equipment and cartridge technology are our innovative solution to our customers’ need for higher sensitivity and quicker quantitative results.
Endosafe® nexgen-PTS™: The Endosafe® nexgen-PTS™ is a rapid, point-of-use handheld spectrophotometer that utilizes USP/BET-compliant disposable cartridges for precise, convenient, and real-time endotoxin testing, glucan concentration determination, and Gram identification.
Endosafe® nexgen-MCS™: This multi-cartridge benchtop LAL test equipment addresses the need for higher sample throughput while utilizing the same FDA-licensed LAL cartridge technology as the Endosafe® nexgen-PTS. The Endosafe ® nexgen-MCS™ is proficient at concurrently testing up to five samples within 15 minutes for rapid, quantitative, and accurate endotoxin results.
Endosafe® Nexus™: The Endosafe® Nexus™ delivers rapid, quantitative results in a low-maintenance, high-precision package as the first fully automated robotic system which eliminates high-volume testing variables and unlocks the full potential of our Endosafe® cartridge technology.
BioTek® Plate Readers: We are able to provide an exceptional level of support for BioTek® endotoxin testing equipment due to our partnership with BioTek ®. In addition to selling the BioTek® ELX808IU™ reader, our technical support department qualifies the instrument for compatibility with Endoscan-V™ software and the LAL test.
Vital Science S2, E08: The Life (Saving) Blood of Horseshoe Crabs
Our panel explores the vital role horseshoe crabs play in bacterial endotoxin testing and the ongoing battle to preserve the population.
Frequently Asked Questions (FAQs) on Endotoxin Testing Equipment
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What endotoxin testing equipment is best for my organization?
As bacterial endotoxin testing solutions vary by method, each lab needs to decide for themselves which instruments will work best for them based on through-put, human capital and money and time resources. Charles River offers a variety of LAL test equipment such as: Endosafe® nexgen-PTS™, Endosafe® nexgen-MCS™, Endosafe® Nexus™, and BioTek® Plate Readers.
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Why would my organization choose automated endotoxin testing equipment?
Executing bacterial endotoxin testing on large numbers of samples using traditional methods can be both time-consuming and leave assay results vulnerable to outside influences, such as technician errors and standard curve anomalies. Automated endotoxin testing solutions such as the Nexus™ would allow your technicians to work on other tasks and prevent human error when administering the assay. See how Pfizer uses the Endosafe® Nexus™.
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Where do I find more information?
You may find more information on our Endosafe technical resources page.