Multi-Cartridge Endotoxin Testing System
The Endosafe® nexgen-MCS™ benchtop system is comprised of five individual spectrophotometers built into a unit with a single Ethernet connector that links to your computer running EndoScan-V™ version 5.5.5 or higher, our 21 CFR Part 11 compliant-ready endotoxin measuring software.
Since each cartridge runs independently, you can run your samples as needed and not wait for a full batch of samples for testing, obtaining results in approximately 15 minutes.
Product Validation
with the Charles River Endosafe® nexgen-MCS™
The Charles River Endosafe® nexgen-MCS™ and our FDA-licensed LAL cartridges are validated for bacterial endotoxin testing and can be used for product validation for both previously validated samples and new products.
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PRODUCT DETAILS
- Test multiple samples simultaneously
- Samples run independently, allowing for random access
- High throughput for real-time endotoxin detection results
- Single-step, quantitative LAL testing
- Uses FDA-licensed LAL cartridges
- LAL testing components all included in cartridges
- Results can be analyzed via EndoScan-V™ endotoxin measuring software
- Sophisticated endotoxin detection data management and reporting capabilities
- Samples can be traced to the individual spectrophotometer used to perform endotoxin testing
- Four levels of sensitivity are available as endotoxin testing options: 0.005, 0.01, 0.05 and 0.10 EU/ml
- No microbiology training is required; anyone can run this simple endotoxin detection assay
- System qualification and validation support is provided if needed
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PRODUCT CODES
Product Code Endosafe® nexgen-MCS™ instrument
Power supply
Ethernet cable
One-year warrantyMCS150K Endosafe® nexgen-MCS™ package
nexgen-MCS™ instrument
EndoScan-V™ software
Power supply
One-year warranty
Ethernet cableMCS650K EndoScan-V™ software M1250
Did You Know Endosafe® LAL Cartridges
Are a Compendial BET Method?
FDA-licensed Endosafe® LAL cartridges are a kinetic chromogenic LAL method as specified in the EP/USP and JP. See the regulatory requirements here:
FDA GuidelinesUSP BET <85> or EP BET <2.6.14>
Frequently Asked Questions (FAQs) About the Endosafe® nexgen-MCS™
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When would you use a Charles River Endosafe® nexgen-MCS™ over a Charles River Endosafe® nexgen-PTS™ for LAL testing?
Both instruments utilize the FDA-licensed Endosafe® cartridge technology for LAL testing, however an Endosafe® nexgen-MCS™ is better for a higher volume of 5 samples at once verses with Endosafe® nexgen-PTS™ can process only one sample at a time.
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How many product samples can you run on a Charles River Endosafe® nexgen-MCS™ per 8-hour shift?
A Charles River Endosafe® nexgen-MCS™ can run at least 120 samples depending on sample composition and sensitivity in an 8-hour shift if continuously running.
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Why would I switch from a kinetic endotoxin testing method to a Charles River Endosafe® nexgen-MCS™?
There are several reasons a Charles River Endosafe® nexgen-MCS™ can benefit your company if you switch from a kinetic method:
- Reduce human error
- Increase data integrity
- Reduce LAL usage
- Purchase less accessories
- Reduce retest rates
- Reduce technician training time
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Is the LAL cartridge technology utilized by the Charles River Endosafe® nexgen-MCS™ is a compendial method?
The LAL cartridge technology utilized is a kinetic chromogenic method which is a compendial method per the USP<85> or EP<2.6.14>.