Multi-Cartridge Endotoxin Testing System

The Endosafe® nexgen-MCS™ benchtop system is comprised of five individual spectrophotometers built into a unit with a single Ethernet connector that links to your computer running EndoScan-V™ version 5.5.5 or higher, our 21 CFR Part 11 compliant-ready endotoxin measuring software.

Since each cartridge runs independently, you can run your samples as needed and not wait for a full batch of samples for testing, obtaining results in approximately 15 minutes.


Product Validation
with the Charles River Endosafe® nexgen-MCS™

Charles River Endosafe nexgen-MCS instrument for rapid and accurate endotoxin detection

The Charles River Endosafe® nexgen-MCS™ and our FDA-licensed LAL cartridges are validated for bacterial endotoxin testing and can be used for product validation for both previously validated samples and new products.

Find out how

  • PRODUCT DETAILS
    • Test multiple samples simultaneously
    • Samples run independently, allowing for random access
    • High throughput for real-time endotoxin detection results
    • Single-step, quantitative LAL testing
    • Uses FDA-licensed LAL cartridges
    • LAL testing components all included in cartridges
    • Results can be analyzed via EndoScan-V™ endotoxin measuring software
    • Sophisticated endotoxin detection data management and reporting capabilities
    • Samples can be traced to the individual spectrophotometer used to perform endotoxin testing
    • Four levels of sensitivity are available as endotoxin testing options: 0.005, 0.01, 0.05 and 0.10 EU/ml
    • No microbiology training is required; anyone can run this simple endotoxin detection assay
    • System qualification and validation support is provided if needed
       

    View the product sheet

  • PRODUCT CODES
    Product Code
    Endosafe® nexgen-MCS™ instrument
    Power supply
    Ethernet cable
    One-year warranty
    MCS150K
    Endosafe® nexgen-MCS™ package
    nexgen-MCS™ instrument
    EndoScan-V™ software
    Power supply
    One-year warranty
    Ethernet cable
    MCS650K
    EndoScan-V™ software M1250

Did You Know Endosafe® LAL Cartridges
Are a Compendial BET Method?

Charles River's comprehensive biologic testing solutions includes stability testing.

FDA-licensed Endosafe® LAL cartridges are a kinetic chromogenic LAL method as specified in the EP/USP and JP. See the regulatory requirements here:

FDA Guidelines
USP BET <85> or EP BET <2.6.14>

 

Frequently Asked Questions (FAQs) About the Endosafe® nexgen-MCS™