Microbial Detection Instruments for Laboratory Automation

Robust, easy-to-use Celsis® systems reduce time to result for quarantined product, achieving shorter production cycles and improved market responsiveness. The advantages of earlier notice of contamination, faster recovery time, and a reduction in your lab waste, water usage and energy consumption are seen with substantial savings in working capital and inventory expenses.

  • Benefits of Laboratory Automation Systems

    While rapid microbiology yields significant operational improvements when knowing intermediate process samples and final products are free of contamination, equipment that delivers laboratory automation capabilities also provide additional process and regulatory compliance benefits.

  • Laboratory Automation Reduces the Risk of Human Error

    Laboratory automation equipment can help quality control departments minimize the risk of human error during manual test methods and data integrity concerns when reporting and archiving test data. Traditional test methods often require the lab technician to perform multiple, sometimes complex, preparation steps when performing even routine assays.

    Additionally, even certain rapid microbiology equipment suppliers require manual input steps, such as staining, labeling, and sequential incubation periods prior to rapid analysis. With each additional manual step, the risk of human error is compounded while the overall efficiency of the process is reduced.

    Celsis® systems preserve current, validated, and standardized test preparation protocols while also automating the injection, timing, and analysis of samples once loaded into the system. Up to 120 assays per hour can be loaded and set for analysis, allowing lab staff to perform other activities while the instrument handles the remainder of the assay and automatically reporting the results.

  • Ensuring Data Integrity with Automated Laboratory Test Results

    Data integrity is a constant concern for laboratories, with increasing scrutiny and pressure by regulators to adopt better and more secure methods for handling data. Traditional test methods, which are prone to subjectivity in the interpretation of results, such as visual turbidity checks during sterility testing, or colony enumeration in plate count based bioburden tests, are at the forefront of regulatory questions.

    Moreover, since these methods require lab personnel to score the result, there is a further risk of transcription error when those results are recorded into records or a laboratory information management system (LIMS). Many microbiology equipment suppliers may provide an instrument that provides a rapid result, but still many require additional input to confirm a reported result against potential false positives or interferences with the technology.

    Celsis® rapid microbial detection instruments provide presence/absence results, triggered by a reaction that is set against each product’s baseline reading. Since this is an enzyme-catalyzed reaction that only occurs in the presence of microbial ATP, there is no subjectivity in the positive or negative interpretation of the result.


Our Rapid Microbial Detection Systems for Laboratory Automation

Celsis Advance II instrument for rapid microbial detection

The Celsis Advance II™ system is designed to deliver definitive results quickly. Capable of running 120 assays per hour, high throughput manufacturers can cut days off their production cycles and reduce working capital requirements.


Celsis Accel system for rapid microbial detectionThe Celsis Accel® system takes the robustness and ease of use of the widely adopted Celsis Advance II™ platform and packages it into a small footprint. With a throughput of 30 assays per hour, this system is specifically designed for small and mid-sized pharmaceutical, home, and beauty product manufacturing facilities.


celsis adapt system for rapid microbial detectionThe Celsis Adapt™ is an accessory instrument for Celsis® rapid detection systems, intended to prepare and concentrate samples containing components that interfere with the background and ATP-bioluminescence detection signal, expanding the application portfolio for Celsis® luminometers.


Considering a rapid microbial method (RMM) for your lab?

Quality control analyst counting plates used in a Traditional incubation plate methodMany labs struggle with determining which RMM is appropriate for them and how to begin the selection process. Fortunately, we've put together the resources to help you decide.

Access the RMM resources

Frequently Asked Questions (FAQs) About Laboratory Automation

  • What is laboratory automation in quality control?

    Laboratory automation involves the usage of instruments, robotics, or software to control repetitive, standardized, or error-prone tasks. Since quality control testing involves operation under strictly controlled protocols, deviation from these protocols, whether accidental or intentional, poses an impact to the integrity of quality control test data and, ultimately, the decisions made based on that data.

    Rapid microbial detection methods such as Celsis® utilize automated processes to ensure the benefits of fast microbial detection results are combined with the benefits of laboratory automation.

  • How does laboratory automation benefit quality control?

    In the quality control laboratory setting, automation reduces the risk of human error, increases data integrity, and streamline routine testing to increase throughput of analyses. Just as in other manufacturing sectors, such as the automotive or aviation industries, an automated laboratory can reduce deviations, reduce operating costs, and maximize productivity. Laboratory automation also assists in the collection and preservation of test results when rapid microbial detection also employ automated results exporting.

  • How do Celsis instruments automate rapid microbial detection?

    Celsis® rapid microbial detection instruments provides automated analysis of samples, handling the timed injection of ATP-bioluminescence reagents, measuring the reaction results, displaying of results, and exporting of data.

  • What is the benefit of using Celsis laboratory automation systems?

    The automated nature of the reagent handling and analysis used by Celsis® rapid microbial detection instruments means that additional human input is not necessary. Other rapid microbiology equipment suppliers require a laboratory technician to perform additional steps such as staining, incubating, or even visual analysis of results. Celsis® microbial detection instruments control the entire analysis once loaded into the instrument. The results are provided within one hour after loading as a confident Presence/Absence result, and do not require further analysis or confirmation by laboratory staff.

    Lab automation greatly reduces the chance of human caused errors in the analysis, eliminates data integrity concerns over results interpretation, and maintains a high throughput environment in the laboratory by reducing additional work.