MALDI-TOF Instrumentation Combined with Accugenix® Microbial Database

Based on MALDI-TOF mass spectrometry, the MALDI Biotyper has become widely accepted across industry segments as the next generation of microbial identification. While conventional biochemical identification takes time-consuming incubation and ancillary pretests, the MALDI-TOF Axcess® System for microbial identification allows for nearly instantaneous organism ID of isolated colonies from a plate.

Axcess system Bruker target plate
An Axcess® System target plate for MALDI preparation.

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Axcess® System Features

  • Bruker MALDI Biotyper: Automated self-cleaning, silent bench-top MALDI-TOF system with enhanced peak resolution, sensitivity and performance.
  • Accugenix® MALDI-TOF Reference Libraries: The largest curated MALDI-TOF microbial database providing relevant identifications of microorganisms commonly recovered in aseptic and non-sterile manufacturing environments. 
  • Accugenix® MALDI-TOF Identification Reports: Clear ID interpretation allows you to make confident operational decisions.
  • No-Match Sample Guarantee: Complimentary AccuPRO-ID® service to test samples that fail to yield a successful species identification at your location.
  • Backup Identification System: If your Axcess® system should unexpectedly go out of service, you can send your samples to your local Accugenix® facility. Although the likelihood of this occurring is rare, we give you the ability to continue your operations and avoid manufacturing delays. 
  • Security: Our IT approach is purposely designed with multiple redundancies to protect your data and to ensure continuity of service 24/7.
  • Tracking and Trending through Our Customer Web Portal: The Accugenix® Customer Web Portal makes it easy to get a glimpse of your environmental control data, past and present. Filterable reports help you note significant changes in microbial flora when investigating excursions or conducting root cause determinations.
  • System Throughput: Workflow analysis has shown that 1 target plate containing 96 spots each can yield results in 15 minutes, compared to other MALDI-TOF instrumentation that can take up to 45 minutes for the same workload or phenotypic systems that can take up to 18 hours of incubation time for biochemical reactions to occur.
  • Specifications
    System Order Code

    Axcess® sirius one MALDI Biotyper package
    Starter kit for MALDI-TOF MS
    Barcode scanner for MALDI Biotyper
    Reference physiocare pack (tips and pipettes)
    Software package MALDI Biotyper Compass HT
    Compliance Assistance Module

    Axcess® sirius MALDI Biotyper Package
    The sirius package includes all the features and accessories as the Axcess® sirius one MALDI Biotyper package, with the added benefit of both positive and negative ion mode for microbial identification and future applications.
    Axcess® MALDI Biotyper-CM Reagents
    Bacterial test standard (BTS)
    Matrix HCCA
    MSP 96 steel target plate
    MSP adapter for MALDI Biotarget
    MALDI Biotarget 96 disposable target plate 20/pk
    Conidia IDFP fungi agar plates 20/pk


    Axcess® Startup Package
    The Axcess® Startup Package is available with the initial Axcess® instrument purchase. It includes the Bruker IQ/OQ/PQ, Charles River SQ/MV, and Axcess® authorization and licensing for one year. Required with purchase. 
    Axcess® Annual Instrument Service Agreement Options
    Complete CARE
    Complete CARE priority plus
    Annual service contract gold
    Annual OQ/PV with service agreement
    Annual OQ/PV without service agreement
    Warranty plus
    On-site Training (per day)
    Software qualification/methods validation
    AXC 404B
  • Partnership Agreement with Bruker to Sell the Axcess® System

    On April 15, 2013, Charles River was pleased to announce a partnership with Bruker to provide rapid, accurate microbial identifications to the industrial microbiology market, including pharmaceutical, biopharmaceutical, personal care and other manufacturing industries. Through this agreement, the Charles River Endotoxin and Microbial Detection division will sell the Axcess® System, an offering that combines the Bruker MALDI Biotyper system with a custom data analysis software solution that allows instantaneous access to the Accugenix® microbial database for identifications.

Frequently Asked Questions About MALDI-TOF for Microbial Identification