Overview

Fully understanding the background genetics of a research animal colony is a key element in designing and implementing a successful breeding plan. Charles River offers an array of off-the-shelf and custom-designed SNP panels designed to do everything from detecting a genetic contamination to fine-mapping a transgene insertion point.

Panels

  • Mouse 384 SNP Complete Background Analysis Panel
  • Mouse 128 SNP C57BL/6 Substrain Panel
  • Mouse and Rat 32-Marker Assay for Contamination Detection

Applications

  • Verification of inbred and outbred backgrounds
  • Detection of genetic contamination and drift
  • Assessment of genetic diversity in outbred animal models
  • Relatedness testing
  • Cell line characterization
  • Linkage analysis
  • Mutation mapping
  • Transgene insertion site mapping
  • Recombination event detection