Rodent Infectious Agents
Lab animal infectious agent PCR testing is used to identify viral, bacterial, fungal, and parasitic agents in your animal colonies. Services are available for screening colony animals directly, indirect screening via environmental sampling or exhaust air dust (EAD™) testing, and screening cell lines and research biologics.
PCR assays are available as panels that cover all commonly excluded or reported pathogens. However, panel customization and single agent testing are available.
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Rodent and Rabbit Infectious Agents
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Viruses
- Ectromelia Virus (Mousepox)
- Filovirus (FV)
- Guinea Pig Adenovirus (GpAV, GAV)
- Guinea Pig Cytomegalovirus (GpCMV)
- Hantaviruses (Hantaan, Prospect hill, Puumala, Dobrava, Seoul, Sin Nombre, etc.)
- Lactate Dehydrogenase Elevating Virus (LDV, LDHV)
- Lymphocytic Choriomeningitis Virus (LCMV)
- Mouse Adenovirus (MAdV-1, MAdV-2, MAV)
- Mouse Cytomegalovirus (MCMV)
- Mouse Hepatitis Virus (MHV)
- Mouse Parvoviruses (MPV-1, MPV-2, MPV-3, MVM)
- Mouse Rotavirus (Epizootic Diarrhea of Infant Mice; EDIM)
- Mouse Thymic Virus (MTV, MTLV)
- Murine Chapparvovirus (MuCPV)
- Murine Norovirus (MNV)
- Pneumonia Virus of Mice (PVM)
- Polyoma Viruses (Polyoma Virus, K Virus [Murine Pneumotropic Virus])
- Rabbit Caliciviruses (Rabbit Hemorrhagic Disease Virus [RHDV], European Brown Hare Virus, Rabbit Calicivirus)
- Rat Parvoviruses (RPV-1, RPV-2, RMV, RV [KRV], H-1)
- Rat Polyomavirus-2 (RPyV2)
- Rat Rotavirus (Infectious Diarrhea Of Infant Rats; IDIR)
- Reovirus (REO-3)
- Sarbecoviruses (SARS-CoV-1, SARS-CoV-2 aka COVID-19)
- Sendai Virus (PI-1, SV)
- Sialodacryoadenitis Virus (RCV, SDAV)
- Simian B Virus
- Simian Virus 5 (SV5, PI2, canine parainfluenza virus)
- Theiloviruses (MEV [TMEV], RTV [GDVII])
- Zika Virus (ZIKV)
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Bacteria
- Beta-Haemolytic Streptococci (BHS)
- Bordetella bronchiseptica
- Filobacterium rodentium (CAR Bacillus)
- Citrobacter rodentium (Citrobacter freundii biotype 4280)
- Clostridium piliforme (Tyzzer's disease, CPIL)
- Corynebacterium bovis
- Corynebacterium kutscheri (Pseudotuberculosis)
- Encephalitozoon cuniculi (ECUN, E. cuniculi)
- Helicobacter species
- Klebsiella species (K. oxytoca, K. pneumoniae)
- Mycoplasma pulmonis
- Pasteurella multocida
- Rodentibacter
- Pneumocystis (P. murina, P. carinii, P. wakefieldae, P. oryctolagi)
- Proteus mirabilis
- Pseudomonas aeruginosa
- Salmonella (S. enterica, various subspecies and serotypes)
- Staphylococcus aureus
- Streptobacillus moniliformis (Haverhill fever, rat bite fever)
- Streptococcus pneumoniae
- Treponema paraluiscuniculi (Treponema cuniculi, rabbit syphilis)
- Tuberculosis (TB)
- Parasites
Infectious Agent Sampling
- Direct Animal Sampling
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Exhaust Air Dust (EAD™)
EAD™ service detects viruses, bacteria, and parasites by screening ventilated caging systems. Additionally, this method overcomes the known limitations of soiled-bedding sentinels for detecting certain rodent infectious agents.
- Environmental Prevalent PRIA®
- Environmental Surveillance Plus PRIA®
- Environmental Complete Mouse/Rat PRIA®
- Custom Environmental PRIA®
- Single Agent Test (individual or add-on)
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Frequently Asked Questions (FAQs) About Lab Animal Infectious Agent Testing
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When is lab animal infectious agent testing used?
Common applications for rodent infectious agent testing include:
- Outbreak investigation
- Alternative health monitoring
- Cell line and research biologics screening
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What is the prevalence of infectious agents in laboratory mice and rats?
Periodic health screening of laboratory animals is essential for detecting unwanted infections and their consequences. The risk of infection for any given agent is its prevalence; other factors being equal, a prevalent agent is more likely than a rare one to be introduced to a research facility and result in infection. Read the whitepaper, Contemporary Prevalence of Infectious Agents in Mice and Rats to learn more.