Triple-Immunodeficient Mouse Model

Triple-immunodeficient models are produced in isolators to provide the high-level biosecurity environment required for animals lacking a normal host defense mechanism. Our NCG mouse is triple-immunodeficient and available for your oncology, immunology, regenerative medicine, and infectious disease research.

Uniquely created using CRISPR-Cas9 technology to alter the Prkdc and Il2rg genes, our NCG mouse is more immunocompromised than commonly used immunodeficient mouse strains, including SCID and nude mice.*

*CRISPR/CAS9 used under licenses to granted and pending US and international patents from The Broad Institute and ERS Genomics Limited.