Nude Mouse Models

Caused by a genetic mutation, nude mouse models lack a normal immune system and thymus gland. They have a repressed immune system due to reduced number of T cells. Nude mice are ideal for tumor and tissue studies because they have no rejection responses and are hairless, making it easier to identify tumors.

Charles River immunodeficient animal models are produced in flexible-film and semi-rigid isolators. This approach provides the high-level biosecurity environment required for animals lacking a normal host defense mechanism. Our portfolio includes inbred and outbred athymic nude mice.

Charles River maintains five different live nude mouse model strains: