Ecotoxicology Testing

Ecotoxicology data is a fundamental requirement for registration submissions in a range of industries, including agrochemicals and industrial chemicals. They also form the basis of Environmental Risk/Impact Assessments (ERA and EIA) for both human and veterinary pharmaceuticals.

We have extensive experience in the design and conduct of both terrestrial ecotoxicology and aquatic ecotoxicology studies.

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Our portfolio includes studies to assess the toxicity of test articles to a range of species, including:

Blue and silver zebra fish used in aquatic toxicity studies.

  • Avian
  • Waste-water bacteria
  • Algae, aquatic, and terrestrial plants
  • Daphnia and fish
  • Soil microorganisms
  • Bees
  • Non-target arthropods
  • Earthworms
  • Freshwater and marine species

We also provide a full analytical service for the method validation and routine analysis required in support of many aquatic studies.

Aquatic Species

  • Activated sludge respiration inhibition (OECD 209)
  • Algal growth inhibition (freshwater and marine) (OECD 201)
  • Acute and prolonged toxicity to Daphnia magna (OECD 202, OECD 211)
  • Acute (96-hour) and prolonged toxicity to cold- and warm-water fish (e.g., rainbow trout, bluegill sunfish, carp, fathead minnow, and zebrafish) (OECD 203)
  • Fish embryo toxicity test (FET test) (OECD 236)
  • Fish, toxicity test on egg and sac-fry stage (OECD 212)
  • Fish early life stage (OECD 210)
  • Radiolabeled (or cold) bioaccumulation and/or metabolism in fish (OECD 305)
  • Lemna sp. growth inhibition (OECD 221)
  • Acute and prolonged sediment water toxicity test to Chironomus riparius (OECD 235, OECD 218, OECD 219)
  • Sediment-water toxicity test with Lumbriculus (OECD 225)

Terrestrial and Avian Species

  • Acute and reproduction toxicity to earthworms (OECD 207, OECD 222)
  • Acute oral and contact toxicity to honeybees (OECD 213, OECD 214)
  • Acute contact and oral toxicity to bumblebees (OECD 246, OECD 247)
  • Acute toxicity to parasitic wasp and predatory mite (basic and extended)
  • Collembolan reproduction in soil (Folsomia candida) (OECD 232)
  • Avian acute oral, dietary, and reproduction in Japanese Quail or Bobwhite (OECD 223, OECD 205, OECD 206) (other avian species are available)
  • Plants, seedling emergence and growth (OECD 208)
  • Plants, vegetative vigor (OECD 227)


Ask an Expert

Your terrestrial ecotoxicology and aquatic ecotoxicology data is a crucial element of your journey to registration. Missing a submission deadline could delay your entry to market, or even give your competitor the opportunity to build market share. Ensuring that you have the data you need to submit a comprehensive dossier on time is vital. We are ready to support you in this process.

Frequently Asked Questions (FAQs) About Ecotoxicology Testing

  • What ecotoxicology studies are required to register an agrochemical product?

    You will need a range of aquatic ecotoxicology and terrestrial ecotoxicology studies in your program to assess the general adverse effects of your product (AI and formulations) on ecosystems, depending on the registered uses of your product and the type of active (e.g., pesticide or chemical). These tests will include assessing the effects on aquatic (algae and higher plants) and terrestrial organisms (earthworms, bees, and other beneficial arthropods, avian species), as well as soil effects such as seed germination/plant biomass production, soil organisms, and an assessment of potential for groundwater contamination by the active or its metabolites.

  • How should I assess the ecotoxicity of my pesticide?

    You may need to perform a range of different studies. The exact program design will depend on several factors, including the class of active substance, the stability of the formulation, the metabolites formed, and more.

  • What are ecotoxicology and environmental safety studies?

    Ecotoxicology and environmental safety studies can be used to assess the potential effects of a chemical in the environment. Environmental Fate studies help us to understand how the chemical substance behaves within various environmental scenarios recreated under laboratory conditions.

  • What is ecotoxicology of human pharmaceuticals?

    As human pharmaceuticals undergo biotransformation within the body before excretion, terrestrial and aquatic ecotoxicology testing can be used to assess the impact of pharmaceutical metabolites once they enter the environment.