Ecotoxicology Testing

Ecotoxicology data is a fundamental requirement for registration submissions in a range of industries, including agrochemicals and industrial chemicals. They also form the basis of Environmental Risk / Impact Assessments (ERA & EIA) for both human and veterinary pharmaceuticals.

Charles River has extensive experience in the design and conduct of ecotoxicology studies and our portfolio includes studies to assess the toxicity of test articles to a range of species, including:

Photo of a group of blue and silver Zebra fish in a tank.

  • Avian
  • Waste-water bacteria
  • Algae, aquatic and terrestrial plants
  • Daphnia and fish
  • Soil microorganisms
  • Freshwater and marine species

We also provide a full analytical service for the method validation and routine analysis required in support of many of the aquatic studies.

Plant & Aquatic Species

  • Activated sludge respiration inhibition (OECD 209)
  • Algal growth inhibition (freshwater and marine) (OECD 201)
  • Acute and prolonged toxicity to Daphnia magna (OECD 202, OECD 211)
  • Acute (96-hour) and prolonged toxicity to cold- and warm-water fish (e.g., rainbow trout, bluegill sunfish, carp, fathead minnow, zebrafish) (OECD 203)
  • Fish embryo toxicity test (FET test) (OECD 236)
  • Fish, toxicity test on egg and sac-fry stage (OECD 212)
  • Fish early life stage (OECD 210)
  • Radiolabeled (or cold) bioaccumulation and/or metabolism in fish (OECD 305)
  • Lemna spp. growth inhibition (OECD 221)
  • Acute and prolonged sediment water toxicity test to Chironomus riparius (OECD 235, OECD 218, OECD 219)
  • Sediment-water toxicity test with Lumbriculus (OECD 225)

Other Species

  • Acute and reproduction toxicity to earthworms (OECD 207, OECD 222)
  • Collembolan reproduction in soil (Folsomia candida) (OECD 232)
  • Plants, seedling emergence and growth (OECD 208)

Biodegradation

Ecotoxicology Frequently Asked Questions (FAQs)