Overview

Charles River offers molecular pathology services that include in situ hybridization (ISH), real-time PCR (rt-PCR) and quantitative PCR (qPCR), performed by a staff with a strong background in molecular biology and histopathology.

Our high level of integration means we can relate gene expression to tissue histomorphology in both normal tissues and therapeutic models of disease, providing valuable functional genomics information. The end result is the best possible interpretation and troubleshooting of molecular-based tools applied to toxicological pathology issues.

Molecular Pathology Services

  • Procurement, embedding and sectioning of study tissues
  • Synthesis of DNA and RNA probes (isotopic and non-isotopic)
  • Optimized hybridization
  • Histological evaluation by board-certified pathologists
  • Reporting with representative color photomicrographs