Overview

Rats and mice are the rodent species routinely used because of their susceptibility to toxic challenge, tumor induction, and carcinogenicity. In addition, we have a vast amount of background information available on their survival, physiology, pathology and susceptibility to different test items. The rabbit is a particularly useful animal model for assessing ocular and dermal irritation and is also the primary nonrodent species for developmental toxicity studies.

Rabbit Housing Facility in Edinburgh

  • ROUTES OF ADMINISTRATION
    • Oral: gavage, capsule, diet
    • Dermal
    • Intraocular/intravitreal
    • Intramuscular
    • Inhalation
    • Intranasal
    • Infusion
    • Intravenous
    • Intraperitoneal
    • Penile/vaginal
    • Rectal
    • Other nonstandard routes by discussion
  • STUDY DESIGNS
    • Acute
    • Subchronic
    • Chronic
    • Developmental and reproductive
    • Juvenile
    • Carcinogenicity