Charles River performs ADME, pharmacokinetic, bioequivalence, residue depletion and target animal safety studies in compliance with EU, VICH, US and Japanese regulations.
We have experience in formulating doses ranging from aquatic-based solutions to oil-based suspensions. Our modern facilities offers enough housing capacity for over 200 lactating cattle. Charles River also offers an integrated analytical service for clinical pathology, residue analysis, and metabolite profiling and identification.
Tolerance Testing in Target Animals
Our experts can design tolerance studies in target animals to meet specific requirements for regulatory submissions. Flexibility in protocols allows us to pay special attention to the in-life use of the product with careful selection of dose levels and animal group sizes.
- Pig (including neonatal)
- Marine and freshwater fish
Routes of Administration
- Topical and dermal
- Oral (dietary, capsule, or gavage)